2010 to 2017 Saw Increase in Uterine Cancer Mortality Rates

FRIDAY, May 6, 2022 (HealthDay News) — Uterine cancer mortality increased from 2010 to 2017, with a larger increase seen for nonendometrioid uterine carcinoma, according to a study published online May 5. JAMA Oncology,

Megan A Clark, PhD, from the National Cancer Institute in Rockville, Maryland, and colleagues estimated histologic subtype- and stage-specific uterine cancer mortality by race and ethnicity in a cohort study. Data were included for 208,587 women diagnosed with uterine cancer during 2000 to 2017 (7.7 percent Asian, 9.7 percent Black, 11.1 percent Hispanic, and 71.5 percent White).

The researchers found that 16,797 uterine cancer deaths occurred between 2010 and 2017, for a hysterectomy-corrected mortality rate of 15.7 per 100,000 person-years. Overall, hysterectomy-corrected rates were highest among Black women, according to histologic subtype and stage of diagnosis. Among all women, there was a 1.8 percent annual increase in mortality for uterine corpus cancer from 2010 to 2017 and a 2.7 percent increase in mortality for non-endometrioid carcinoma; The increase was seen in Asian, Black, Hispanic and White women (3.4, 3.5, 6.7 and 1.5 percent, respectively). Endometrioid carcinoma mortality remained stable during the same period.

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“Our study suggests racial disparities in uterine cancer mortality that appear to be multifactorial, including a higher incidence of aggressive subtypes and poorer outcomes independent of subtype and stage among black women,” the authors write.

One author disclosed financial ties to several pharmaceutical companies.

Abstract/full text (subscription or payment may be required)

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